Toxicity and Deficiency Impact of Niacin

Disorders that may occur in the body because of lack or deficiency of niacin are:
* Nervous disorders: a deficiency of this vitamin, can cause nervousness, anxiety, insomnia, depression, and the worst dementia.
* Problems in the digestive system: diarrhea, indigestion, itching in the rectum, thickened tongue and mouth sores. If the deficiency is minimal, appears to have bad breath.
* In the past, lack of vitamin B3, caused a disease called Pellagra. This happened because the power of the population was based on corn, cereal lacking tryptophan. Today this disease is eradicated in developed countries, but exists in countries in Africa and Asia.
The situations where niacin supplementation is necessary are:
* Poor circulation: in the limbs, hands and legs, niacin relaxes blood vessels, therefore useful for blood to flow optimally.
* Arthritis: Joint inflammation helps people suffering from rheumatoid arthritis.
* High Cholesterol: vitamin lowers blood cholesterol levels.
* Diabetes I (insulin-dependent): the administration of niacin in the beginning of this disease, slows the progression of it.
* Ringing in the ears or tinnitus: it can be helpful with niacin supplementation, thus decreasing the ringing or noise experienced by people with this problem.
* Malabsorption syndrome
* Hemodialysis and peritoneal dialysis
Toxicity
Niacin supplements should always be administered under medical prescription and control, as its excess can cause severe stomach and liver damage, as well as reddening of the skin (caused by the action of hormones called prostaglandins components that cause dilation of blood vessels) .
The signs of poisoning are:
* Increased blood glucose levels.
* Liver disease (jaundice: yellowing of skin and mucous membranes)
* General itching
* Development of ulcers
Hypertension, gout and diabetes may become more widespread use of niacin supplements.
Have been established tolerable upper intake levels (tolerable upper intake Levels: UL) to prevent the risk of toxicity with vitamin B3. The adverse effects of higher intakes are increased to the maximum level tolerable.
Where do we find the vitamin B3 or Niacin?
Niacin is absorbed in the intestine so it is important that there is no constipation or diarrhea.
Brewer’s yeast, whole grains, nuts, legumes and seaweed provide us with the necessary amount of vitamin B3 (10 to 20 mg. Day).
In case of stomach ulcers, glaucoma and liver failure is important not to exceed the 30 mg daily. Consult then the doctor or specialist first.
Credit to: Cuadros Jiménez
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